you might modify the Windows Registries of the remote computers on your domain usingGroup Policy Preferenceson theDomain Controller.
In this article, we show you two methods to manage Windows Registries for remote computers on your domain.
As mentioned before, there are two methods to manage and edit Windows Registries in an Active Directory Domain.

opt for Registry value by checking the adjacent box, and then clickFinish.
This will import the remote Registry value(s) to the local server.
This will launch the valuesPropertiesdialog box.

Make the necessary changes and then clickApplyandOk.
pop in in gpmc.msc to launch the Group Policy Management Console.
Enter a custom name for the GPO and clickOk.

Right-nudge the new GPO and clickEdit.Edit the GPO
Right-click Registry, expandNew, and then click Registry Item.
Enter the path for the value that you want to manage.
Note:Do not enter the name of the Hive in the key path.

Enter the precise name of the value that you want to create/modify.
Thus, you might create a GPO and apply it to the Organizational Unit to make the necessary changes.
We say so as it includes the accurate paths, current values, and the value punch in.
This reduces the chances of the administrator making a mistake.
A mistake in modifying, deleting, or creating a Windows Registry value can drastically impact the outcome.
The computers OS could be damaged permanently.
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source: www.itechtics.com