MicrosoftWindowsWindows 10
MsMpEng.exe is the core process of Windows Defender.
Windows Defender comes pre-installed on Windows 10.
Sometimes MsMpEng.exe starts utilizing 100% of CPU and Disk.

While this is happening, the system becomes slow or even stops responding.
In that case, it should be restricted/disabled to bring back to its normal state.
But after disabling it, installanother good Antivirus softwareso your systems protection will not suffer.

To disable Defender, follow below steps.
But again dont forget to install another good security software for your systems protection.
So add the MsMpEng.exe file in the list of Excluded files and locations.

This will cut the load on CPU as Defender wont scan for its own directory.
Apply below steps to do this.
Otherwise, you will have usual load for every process.
These steps can be followed for all the directories and folders on which Windows Defender gets stuck while scanning.
But it will cut the scan speed of Windows defender than usual.
But slow scan speed is better than having high CPU usage.
Apply below steps to set the affinity in limited mode.
Hopefully, these solutions will work for you.
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source: www.itechtics.com