This is probably due to the fact that your Outlook Data File (OST) keeps growing.
If you are running out of storage space in C drive, this is the article for you.
TIP:Learn more about thedifference between PST and OST Outlook data file formats.

Hence, many users are reluctant to move the OST file from its default location.
A loaded system drive could potentially result in degraded system performance and cause lag.
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source: www.itechtics.com