Outlook Data File Cannot Be Accessed Error 0x8004010F (Solved)

This error usually occurs due to corrupt Outlook profile or inaccessible Outlook data files (OST or PST).

Here is how to fix this problem.

Repairing Outlook Data File and Creating a New Outlook Profile is very helpful to fix such problems.

Lets first Turn off the antivirus utilities, and disconnect from VPN if configured.

The scanpst.exe tool is typically located in the Outlook installation directory.

Note: This file is the one displaying the Outlook Data File Cannot Be Accessed error.

After selecting the file, press the Start button.

The tool will begin scanning the PST file for any errors or inconsistencies.

Lets first identify the current location of your default Outlook data file and then create a new Outlook profile.

locate the default Outlook data file.

Create a new Outlook profile.

If this is the scenario, you must suspend the Windows Defender Firewall.

Now verify if there is no more error while trying to send or receive an email in Outlook.

In addition, Open Outlook in Safe Mode: Press Win + R, typeOutlook/safe, and press Enter.

Go to File > Options > Add-ins.

Here Disable suspicious or unnecessary add-ins.

This helps identify if a problematic add-in is causing the issue.

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