Solved: Mouse left click button not working windows 10

If you are using a wireless mouse, replace its batteries and check the status.

Start your machine inSafe Modeand see if the mouse click not working issue persists.

If not there are chances of any third-party program conflict causing the issue.

Reinstall the Mouse driver

Again an outdated or corrupted machine driver can cause such issues.

Running the build-insystem file checkerutility can fix these types of problems.